Ultram (tramadol) can be used for the treatment of moderate to severe pain, while the expected release tablets of Ultram are prescribed for patients that need round the clock treatment of chronic pain. Make sure you discuss your personal and family medical history with your health care provider to make sure you will get all the benefits of the treatment. The following conditions are especially important to mention: a history of a suicide attempt, kidney disease, liver disease, a history of depression or mental illness, any stomach disorder, or any other conditions that may be of importance. Your doctor will need to know as much as possible about other drugs you are already taking or are planning on taking, as interactions can affect the success of your treatment. The following meds are supposed to be reported warfarin, pain medications, St. John's wort, muscle relaxants, cold medicine, ketoconazole, depression or anxiety meds, carbamazepine, erythromycin, and rifampin. Side effects are very much possible and tend to be mild and short lived. The following ones are most common: dizziness, flushing, constipation, vomiting, loss of appetite, weakness, drowsiness, nausea, and sleep problems.